Intismeran Autogene Plus Pembrolizumab Versus Pembrolizumab Alone in High-Risk Resected Melanoma: 5-Year Update of the Randomized Phase IIb KEYNOTE-942 Study. ↗
KEYNOTE-942 five-year follow-up: RFS and DMFS benefit; wide OS CI. Same Phase 2b cohort.
MRNA · 2026-09-08
| Window | Evidence |
|---|---|
| Full melanoma results | Effect size, safety, follow-up |
| Autumn 2026 | Sales, margins, cash |
| PA · 2026 E | Registrational results |
| Norovirus study | Efficacy by cohort |
| Lung studies | Randomized results |
| Flu · 2026–2030 | High-dose comparison; confirmation |
| Debt · 2030 / 2032 | Maturities / refinancing |
| Litigation | Rulings / cash obligations |
mNEXSPIKE: 10 µg; spike NTD/RBD. SPIKEVAX: full spike. Competitors: COMIRNATY, NUVAXOVID. mNEXSPIKE label ↗COMIRNATY ↗NUVAXOVID ↗
SPIKEVAX and mNEXSPIKE: Latest granted patents: US 2041 / Europe 2036; extensions excluded. 2025 10-K ↗
Global sales · USDm · before probability weighting
| Case | Launch / origin | Probability | 2030 E | 2035 E | 2040 E | Peak to 2055 |
|---|---|---|---|---|---|---|
| Bear | 2020 | 100% | 858 | 737 | 498 | 1,650 (2026) |
| Base | 2020 | 100% | 1,771 | 1,524 | 1,174 | 1,896 (2027) |
| Bull | 2020 | 100% | 3,207 | 2,626 | 2,183 | 3,207 (2030) |
65% mature margin · net of royalties
| Region | Volume | Net price / unit, USD | Sales, USDm |
|---|---|---|---|
| European Union | 5,021,274 doses | 55 | 276.2 |
| Other reimbursed markets, mainly Japan/UK/Canada/Australia | 4,338,267 doses | 65 | 282.0 |
| United States | 9,658,549 doses | 100 | 965.9 |
| Year | Bear | Base | Bull |
|---|---|---|---|
| 2026 E | 1,650.0 | 1,800.0 | 1,950.0 |
| 2027 E | 1,583.1 | 1,895.6 | 2,245.7 |
| 2028 E | 1,310.9 | 1,889.9 | 2,622.6 |
| 2029 E | 1,070.2 | 1,837.7 | 2,938.7 |
| 2030 E | 858.5 | 1,770.9 | 3,207.4 |
| 2031 E | 834.3 | 1,670.0 | 2,965.4 |
| 2032 E | 809.1 | 1,596.4 | 2,790.2 |
| 2033 E | 780.9 | 1,536.9 | 2,649.3 |
| 2034 E | 756.8 | 1,530.6 | 2,637.8 |
| 2035 E | 737.1 | 1,524.0 | 2,626.1 |
| 2036 E | 682.4 | 1,448.3 | 2,533.9 |
| 2037 E | 631.4 | 1,375.5 | 2,443.5 |
| 2038 E | 583.8 | 1,305.5 | 2,354.9 |
| 2039 E | 539.5 | 1,238.3 | 2,267.9 |
| 2040 E | 498.2 | 1,173.7 | 2,182.6 |
| 2041 E | 427.8 | 1,067.0 | 2,094.2 |
| 2042 E | 367.4 | 970.2 | 2,009.4 |
| 2043 E | 315.6 | 882.1 | 1,928.3 |
| 2044 E | 271.1 | 802.2 | 1,850.5 |
| 2045 E | 232.8 | 729.5 | 1,776.0 |
| 2046 E | 200.0 | 663.4 | 1,704.6 |
| 2047 E | 171.9 | 603.4 | 1,636.2 |
| 2048 E | 147.6 | 548.8 | 1,570.6 |
| 2049 E | 126.9 | 499.2 | 1,507.7 |
| 2050 E | 109.0 | 454.1 | 1,447.5 |
| 2051 E | 93.7 | 413.2 | 1,389.8 |
| 2052 E | 80.5 | 375.9 | 1,334.4 |
| 2053 E | 69.2 | 342.0 | 1,281.4 |
| 2054 E | 59.5 | 311.2 | 1,230.5 |
| 2055 E | 51.1 | 283.2 | 1,181.7 |
USD millions; EPS in USD/share
| USD millions | 2025-Q3 | 2025-Q4 | 2026-Q1 | 2026-Q2 |
|---|---|---|---|---|
| Revenue | ||||
| COVID sales (combined brands) | ||||
| RSV sales | ||||
| Other revenue | ||||
| Cost of sales | ||||
| Gross profit | ||||
| R&D | ||||
| SG&A | ||||
| Operating income / loss | ||||
| Net income / loss | ||||
| Diluted EPS ($/share) | — | |||
| Cash + marketable investments | ||||
| Operating cash flow | ||||
| Capex (cash outflow) | ||||
| OCF − capex |
Cash includes investments. FCF = OCF − capex.
H1 2026 COGS: $876m settlement charge; $172m excluding charge. July cash payment: $950m.
3 differences
| Metric | Original filing | Latest available | Difference |
|---|---|---|---|
| COVID sales (combined brands) | — | Newly available | |
| Current restricted cash | — | Newly available | |
| RSV sales | — | Newly available |
2026 A/E: actual H1 + estimated H2.
| USD millions | 2026 A/E | 2027 E | 2028 E | 2029 E | 2030 E | 2031 E |
|---|---|---|---|---|---|---|
| Company revenue | 2,100 | 2,385 | 2,791 | 3,317 | 3,918 | 4,418 |
| Cost of sales | 1,700 | 788 | 931 | 1,109 | 1,309 | 1,467 |
| Gross contribution | 400 | 1,597 | 1,860 | 2,208 | 2,609 | 2,951 |
| R&D · Moderna net share | 2,900 | 2,300 | 2,100 | 2,050 | 2,000 | 1,960 |
| Central SG&A | 1,000 | 900 | 850 | 875 | 900 | 900 |
| Operating income | (3,500) | (1,603) | (1,090) | (717) | (291) | 91 |
| Nonoperating | 205 | 187 | 153 | 132 | 124 | 147 |
| Pretax income | (3,295) | (1,416) | (937) | (585) | (167) | 238 |
| Tax | 24 | 40 | 52 | 89 | 156 | 215 |
| Net income | (3,319) | (1,456) | (988) | (673) | (323) | 23 |
| Conditional operating cash flow | (2,062) | (870) | (431) | (143) | 35 | 377 |
| Cash capex | 250 | 200 | 233 | 267 | 300 | 290 |
| Conditional cash · unfinanced | 7,528 | 6,439 | 5,775 | 5,365 | 4,500 | 4,587 |
| Probability-weighted cash · unfinanced | 7,528 | 6,439 | 5,773 | 5,355 | 4,470 | 4,508 |
| USD millions | 2032 E | 2033 E | 2034 E | 2035 E | 2036 E | 2037 E |
|---|---|---|---|---|---|---|
| Company revenue | 4,829 | 5,087 | 5,248 | 5,422 | 5,417 | 5,440 |
| Cost of sales | 1,591 | 1,656 | 1,675 | 1,685 | 1,620 | 1,559 |
| Gross contribution | 3,238 | 3,431 | 3,573 | 3,737 | 3,797 | 3,881 |
| R&D · Moderna net share | 1,920 | 1,880 | 1,840 | 1,800 | 1,720 | 1,640 |
| Central SG&A | 900 | 900 | 900 | 900 | 850 | 800 |
| Operating income | 418 | 651 | 833 | 1,037 | 1,227 | 1,441 |
| Nonoperating | 74 | 60 | 80 | 110 | 150 | 198 |
| Pretax income | 492 | 712 | 914 | 1,146 | 1,376 | 1,639 |
| Tax | 252 | 284 | 306 | 330 | 344 | 362 |
| Net income | 239 | 428 | 608 | 816 | 1,032 | 1,277 |
| Conditional operating cash flow | 588 | 779 | 955 | 1,295 | 1,496 | 1,702 |
| Cash capex | 280 | 270 | 260 | 250 | 230 | 210 |
| Conditional cash · unfinanced | 1,895 | 2,404 | 3,099 | 4,144 | 5,410 | 6,902 |
| Probability-weighted cash · unfinanced | 1,726 | 2,089 | 2,566 | 3,295 | 4,132 | 5,066 |
| USD millions | 2038 E | 2039 E | 2040 E | 2041 E | 2042 E | 2043 E |
|---|---|---|---|---|---|---|
| Company revenue | 5,456 | 5,427 | 5,355 | 5,026 | 4,692 | 4,362 |
| Cost of sales | 1,500 | 1,445 | 1,392 | 1,262 | 1,144 | 1,038 |
| Gross contribution | 3,956 | 3,983 | 3,963 | 3,764 | 3,547 | 3,324 |
| R&D · Moderna net share | 1,560 | 1,480 | 1,400 | 1,300 | 1,200 | 1,100 |
| Central SG&A | 750 | 700 | 650 | 610 | 570 | 530 |
| Operating income | 1,646 | 1,803 | 1,913 | 1,854 | 1,777 | 1,694 |
| Nonoperating | 253 | 316 | 384 | 455 | 528 | 599 |
| Pretax income | 1,899 | 2,118 | 2,297 | 2,310 | 2,305 | 2,293 |
| Tax | 394 | 424 | 459 | 462 | 461 | 459 |
| Net income | 1,505 | 1,695 | 1,838 | 1,848 | 1,844 | 1,835 |
| Conditional operating cash flow | 1,896 | 2,054 | 2,166 | 2,189 | 2,168 | 2,140 |
| Cash capex | 190 | 170 | 150 | 145 | 140 | 135 |
| Conditional cash · unfinanced | 8,608 | 10,492 | 12,508 | 14,552 | 16,581 | 18,586 |
| Probability-weighted cash · unfinanced | 6,100 | 7,220 | 8,414 | 9,595 | 10,737 | 11,845 |
| USD millions | 2044 E | 2045 E | 2046 E | 2047 E | 2048 E | 2049 E |
|---|---|---|---|---|---|---|
| Company revenue | 4,046 | 3,729 | 3,404 | 3,090 | 2,802 | 2,541 |
| Cost of sales | 942 | 855 | 777 | 706 | 641 | 583 |
| Gross contribution | 3,104 | 2,874 | 2,627 | 2,384 | 2,161 | 1,958 |
| R&D · Moderna net share | 1,000 | 900 | 820 | 740 | 660 | 580 |
| Central SG&A | 490 | 450 | 410 | 370 | 330 | 290 |
| Operating income | 1,614 | 1,524 | 1,397 | 1,274 | 1,171 | 1,088 |
| Nonoperating | 670 | 739 | 807 | 874 | 938 | 1,001 |
| Pretax income | 2,284 | 2,263 | 2,205 | 2,148 | 2,109 | 2,089 |
| Tax | 457 | 453 | 441 | 430 | 422 | 418 |
| Net income | 1,827 | 1,810 | 1,764 | 1,718 | 1,687 | 1,671 |
| Conditional operating cash flow | 2,113 | 2,079 | 2,013 | 1,946 | 1,892 | 1,853 |
| Cash capex | 130 | 125 | 116 | 107 | 98 | 89 |
| Conditional cash · unfinanced | 20,569 | 22,522 | 24,419 | 26,258 | 28,052 | 29,815 |
| Probability-weighted cash · unfinanced | 12,930 | 13,997 | 15,035 | 16,047 | 17,043 | 18,035 |
| USD millions | 2050 E | 2051 E | 2052 E | 2053 E | 2054 E | 2055 E |
|---|---|---|---|---|---|---|
| Company revenue | 2,303 | 2,091 | 1,899 | 1,724 | 1,566 | 1,421 |
| Cost of sales | 529 | 481 | 438 | 398 | 362 | 329 |
| Gross contribution | 1,774 | 1,610 | 1,462 | 1,326 | 1,204 | 1,092 |
| R&D · Moderna net share | 500 | 440 | 380 | 320 | 260 | 200 |
| Central SG&A | 250 | 220 | 190 | 160 | 130 | 100 |
| Operating income | 1,024 | 950 | 892 | 846 | 814 | 792 |
| Nonoperating | 1,063 | 1,124 | 1,185 | 1,245 | 1,306 | 1,370 |
| Pretax income | 2,087 | 2,074 | 2,076 | 2,092 | 2,120 | 2,162 |
| Tax | 417 | 415 | 415 | 418 | 424 | 432 |
| Net income | 1,669 | 1,659 | 1,661 | 1,673 | 1,696 | 1,730 |
| Conditional operating cash flow | 1,828 | 1,803 | 1,790 | 1,788 | 1,797 | 1,987 |
| Cash capex | 80 | 74 | 68 | 62 | 56 | 50 |
| Conditional cash · unfinanced | 31,563 | 33,292 | 35,014 | 36,740 | 38,481 | 40,418 |
| Probability-weighted cash · unfinanced | 19,032 | 20,029 | 21,034 | 22,055 | 23,101 | 24,311 |
EPS: spot-share basis.
| USD millions | 2026-Q3 | 2026-Q4 | 2027-Q1 | 2027-Q2 |
|---|---|---|---|---|
| Company revenue | 861 | 705 | 319 | 189 |
| Cost of sales | 359 | 293 | 99 | 53 |
| Gross contribution | 503 | 411 | 220 | 136 |
| R&D · Moderna net share | 800 | 800 | 575 | 575 |
| Central SG&A | 306 | 306 | 225 | 225 |
| Operating income | (603) | (694) | (580) | (664) |
| Nonoperating | 47 | 57 | 52 | 48 |
| Pretax income | (556) | (637) | (528) | (616) |
| Tax | 0 | 0 | 10 | 10 |
| Net income | (556) | (637) | (538) | (626) |
| Conditional operating cash flow | (412) | (493) | (391) | (479) |
| Cash capex | 76 | 76 | 50 | 50 |
| Conditional cash · unfinanced | 8,115 | 7,528 | 7,086 | 6,557 |
| Probability-weighted cash · unfinanced | 8,115 | 7,528 | 7,086 | 6,557 |
| EPS estimate · USD/share | (1.39) | (1.59) | (1.34) | (1.56) |
| USD millions | 2027-Q3 | 2027-Q4 | 2028-Q1 | 2028-Q2 |
|---|---|---|---|---|
| Company revenue | 1,037 | 839 | 363 | 214 |
| Cost of sales | 353 | 282 | 114 | 61 |
| Gross contribution | 685 | 556 | 249 | 153 |
| R&D · Moderna net share | 575 | 575 | 525 | 525 |
| Central SG&A | 225 | 225 | 213 | 213 |
| Operating income | (115) | (244) | (489) | (585) |
| Nonoperating | 44 | 43 | 43 | 39 |
| Pretax income | (72) | (201) | (446) | (546) |
| Tax | 10 | 10 | 10 | 10 |
| Net income | (82) | (211) | (456) | (556) |
| Conditional operating cash flow | 65 | (64) | (317) | (416) |
| Cash capex | 50 | 50 | 58 | 58 |
| Conditional cash · unfinanced | 6,572 | 6,439 | 6,064 | 5,590 |
| Probability-weighted cash · unfinanced | 6,572 | 6,439 | 6,063 | 5,588 |
| EPS estimate · USD/share | (0.20) | (0.53) | (1.14) | (1.39) |
| USD millions | 2028-Q3 | 2028-Q4 | 2029-Q1 | 2029-Q2 |
|---|---|---|---|---|
| Company revenue | 1,235 | 979 | 419 | 246 |
| Cost of sales | 424 | 332 | 131 | 70 |
| Gross contribution | 812 | 647 | 288 | 176 |
| R&D · Moderna net share | 525 | 525 | 513 | 513 |
| Central SG&A | 213 | 213 | 219 | 219 |
| Operating income | 74 | (91) | (443) | (555) |
| Nonoperating | 35 | 37 | 37 | 34 |
| Pretax income | 109 | (54) | (407) | (521) |
| Tax | 22 | 10 | 10 | 10 |
| Net income | 87 | (64) | (417) | (531) |
| Conditional operating cash flow | 227 | 75 | (284) | (399) |
| Cash capex | 58 | 58 | 67 | 67 |
| Conditional cash · unfinanced | 5,758 | 5,775 | 5,424 | 4,959 |
| Probability-weighted cash · unfinanced | 5,756 | 5,773 | 5,420 | 4,952 |
| EPS estimate · USD/share | 0.21 | (0.16) | (1.04) | (1.33) |
| USD millions | 2029-Q3 | 2029-Q4 | 2030-Q1 | 2030-Q2 |
|---|---|---|---|---|
| Company revenue | 1,492 | 1,160 | 486 | 287 |
| Cost of sales | 514 | 395 | 151 | 81 |
| Gross contribution | 979 | 765 | 335 | 207 |
| R&D · Moderna net share | 513 | 513 | 500 | 500 |
| Central SG&A | 219 | 219 | 225 | 225 |
| Operating income | 248 | 34 | (390) | (518) |
| Nonoperating | 30 | 32 | 33 | 30 |
| Pretax income | 277 | 66 | (357) | (488) |
| Tax | 55 | 13 | 10 | 10 |
| Net income | 222 | 53 | (367) | (498) |
| Conditional operating cash flow | 354 | 185 | (277) | (409) |
| Cash capex | 67 | 67 | 75 | 75 |
| Conditional cash · unfinanced | 5,247 | 5,365 | 5,013 | 4,529 |
| Probability-weighted cash · unfinanced | 5,238 | 5,355 | 4,998 | 4,509 |
| EPS estimate · USD/share | 0.54 | 0.13 | (0.92) | (1.25) |
Revenue: owned sales + net INT collaboration income + PA royalties.
| USD millions | 2026 A/E | 2027 E | 2028 E | 2029 E | 2030 E | 2031 E |
|---|---|---|---|---|---|---|
| Proportionate economic revenue | 2,100 | 2,385 | 2,800 | 3,349 | 3,981 | 4,523 |
| Company revenue | 2,100 | 2,385 | 2,791 | 3,317 | 3,918 | 4,418 |
| Proportionate economic cost of sales | 1,700 | 788 | 940 | 1,141 | 1,372 | 1,572 |
| Company cost of sales | 1,700 | 788 | 931 | 1,109 | 1,309 | 1,467 |
| Net INT collaboration income | — | 0 | 12 | 39 | 77 | 129 |
| PA royalties | — | 0 | 3 | 9 | 17 | 26 |
| SBC cash add-back | 450 | 400 | 383 | 367 | 350 | 340 |
| Probability-weighted operating cash flow | (2,062) | (870) | (433) | (151) | 15 | 328 |
| Probability-weighted unlevered cash flow | — | (1,657) | (1,196) | (907) | (746) | (434) |
| Partner milestone cash | 0 | 0 | 0 | 0 | 150 | 150 |
Scenario SOTP · 15 assets · company costs included · 2055 horizon · 411.9m shares
| USD millions, except per share | Bear | Base | Bull |
|---|---|---|---|
| Discount rate | 13% | 11% | 9% |
| COVID franchise: Spikevax + mNEXSPIKE | 3,600 | 8,123 | 16,238 |
| mRESVIA | 214 | 632 | 1,439 |
| mFLUSIVA | 952 | 3,000 | 7,151 |
| mCOMBRIAX | 1,493 | 5,961 | 15,400 |
| mRNA-1403 | (500) | (111) | 1,148 |
| mRNA-3927 | (14) | 97 | 587 |
| INT — adjuvant high-risk melanoma | (534) | 122 | 2,783 |
| INT — surgery-first adjuvant NSCLC | (402) | (304) | 644 |
| INT — residual NSCLC after neoadjuvant therapy | (473) | (353) | 889 |
| INT — high-risk stage I nonsquamous NSCLC | (426) | (425) | 193 |
| INT — high-risk resected RCC | (291) | (285) | 192 |
| INT — resected high-risk muscle-invasive bladder cancer | (291) | (317) | (63) |
| INT — high-risk BCG-naive NMIBC | (259) | (289) | (40) |
| INT — first-line metastatic melanoma | (216) | (254) | (175) |
| INT — first-line metastatic squamous NSCLC | (245) | (237) | 303 |
| Operating asset subtotal | 2,611 | 15,360 | 46,689 |
| Central cost PV · deduct | 17,722 | 18,532 | 21,954 |
| Enterprise residual | (15,111) | (3,172) | 24,735 |
| Estimated net cash adjustment | 4,368 | 4,595 | 4,762 |
| Unfloored equity residual | (10,743) | 1,422 | 29,497 |
| Equity residual / share | (26.08) | 3.45 | 71.62 |
| Floored / share | 0.00 | 3.45 | 71.62 |
Excludes new financing.
Base · USDm
| Program | Success-case PV | Risk-adjusted PV | Development PV | rNPV |
|---|---|---|---|---|
| COVID franchise: Spikevax + mNEXSPIKE | 8,123 | 8,123 | 0 | 8,123 |
| mRESVIA | 632 | 632 | 0 | 632 |
| mFLUSIVA | 3,000 | 3,000 | 0 | 3,000 |
| mCOMBRIAX | 5,961 | 5,961 | 0 | 5,961 |
| mRNA-1403 | 532 | 213 | 324 | (111) |
| mRNA-3927 | 186 | 112 | 15 | 97 |
| INT — adjuvant high-risk melanoma | 1,022 | 869 | 747 | 122 |
| INT — surgery-first adjuvant NSCLC | 441 | 221 | 524 | (304) |
| INT — residual NSCLC after neoadjuvant therapy | 595 | 268 | 620 | (353) |
| INT — high-risk stage I nonsquamous NSCLC | 376 | 132 | 557 | (425) |
| INT — high-risk resected RCC | 381 | 95 | 380 | (285) |
| INT — resected high-risk muscle-invasive bladder cancer | 236 | 59 | 375 | (317) |
| INT — high-risk BCG-naive NMIBC | 246 | 49 | 338 | (289) |
| INT — first-line metastatic melanoma | 123 | 25 | 279 | (254) |
| INT — first-line metastatic squamous NSCLC | 423 | 85 | 321 | (237) |
Adjuvant melanoma only · USD/share
| Rate | 55% | 75% | 85% | 90% |
|---|---|---|---|---|
| 9% | 3.71 | 4.28 | 4.57 | 4.71 |
| 11% | 2.75 | 3.22 | 3.45 | 3.57 |
| 13% | 2.14 | 2.54 | 2.73 | 2.83 |
Assumed raises: cash below $500m → $1.5bn; 5% fees. Uncommitted.
| Case | First raise | Issue price, USD | Gross, USDm | Fees, USDm | New shares, m | Legacy ownership¹ |
|---|---|---|---|---|---|---|
| Bear | 2029-Q4 | 35 | 25,262 | 1,263 | 721.8 | 36.3% |
| Base | — | 70 | 0 | 0 | 0.0 | 100.0% |
| Bull | — | 140 | 0 | 0 | 0.0 | 100.0% |
¹ Financing dilution only; excludes future employee awards.
| Period | Cash before raise | Gross raise | Fees | USD/share | Shares, m |
|---|---|---|---|---|---|
| 2029-Q4 | 395 | 1,163 | 58 | 35.00 | 33.24 |
| 2030-Q2 | 306 | 1,257 | 63 | 35.00 | 35.92 |
| 2030-Q4 | 189 | 1,380 | 69 | 35.00 | 39.42 |
| 2031-Q2 | 364 | 1,196 | 60 | 35.00 | 34.17 |
| 2032-Q1 | (2,617) | 4,334 | 217 | 35.00 | 123.82 |
| 2032-Q4 | 441 | 1,115 | 56 | 35.00 | 31.85 |
| 2033-Q2 | 473 | 1,081 | 54 | 35.00 | 30.90 |
| 2034-Q2 | 143 | 1,429 | 71 | 35.00 | 40.82 |
| 2035-Q2 | 327 | 1,235 | 62 | 35.00 | 35.29 |
| 2036-Q2 | 500 | 1,053 | 53 | 35.00 | 30.08 |
| 2037-Q4 | 429 | 1,127 | 56 | 35.00 | 32.20 |
| 2039-Q1 | 331 | 1,231 | 62 | 35.00 | 35.16 |
| 2040-Q2 | 417 | 1,140 | 57 | 35.00 | 32.58 |
| 2042-Q1 | 480 | 1,074 | 54 | 35.00 | 30.67 |
| 2043-Q4 | 425 | 1,131 | 57 | 35.00 | 32.33 |
| 2045-Q2 | 485 | 1,068 | 53 | 35.00 | 30.53 |
| 2047-Q2 | 472 | 1,082 | 54 | 35.00 | 30.91 |
| 2049-Q4 | 484 | 1,070 | 53 | 35.00 | 30.56 |
| 2053-Q2 | 459 | 1,096 | 55 | 35.00 | 31.31 |
Options netted at August 27 reference price.
| Basis | Shares, m | Bear USD/share | Base USD/share | Bull USD/share |
|---|---|---|---|---|
| Basic · known events | 400.0 | (26.86) | 3.56 | 73.74 |
| Basic + vested overhang | 411.9 | (26.08) | 3.45 | 71.62 |
| Gross 42m equivalents | 442.0 | (24.31) | 3.22 | 66.74 |
Converts: debt treatment. No conversion shares or capped-call asset.
USD millions. Financing reference ↗: $142.77, 2026-08-27.
Maturities: Ares 2030; converts 2032. Lease cash: principal + interest.
| Input | Value | As of | Source |
|---|---|---|---|
| Ares principal | 600.0 USDm | 2026-06-30 | 10-Q ↗ |
| Ares cash interest | 9.2% | 2026-06-30 | 10-Q ↗ |
| Convertible principal | 3,000.0 USDm | 2026-09-01 | 8-K ↗ |
| Convertible proceeds before capped call | 2,957.3 USDm | 2026-09-01 | 8-K ↗ |
| Capped-call premium | 328.8 USDm | 2026-09-01 | 8-K ↗ |
| Lease cash · H2 2026 | 19.0 USDm | 2026-06-30 | 10-Q ↗ |
| Lease cash · 2027 | 19.0 USDm | 2026-06-30 | 10-Q ↗ |
KEYNOTE-942 five-year follow-up: RFS and DMFS benefit; wide OS CI. Same Phase 2b cohort.
Adults 50+; relative efficacy 26.6% versus standard-dose influenza vaccine.
NextCOVE: noninferiority met; overall relative-efficacy CI crossed zero.
Antibody noninferiority met; greater reactogenicity with combination vaccine.
Phase 1/2, n=16, open-label. Metabolic-decompensation estimate favored treatment; CI crossed no effect.
KEYNOTE-942, Phase 2b: RFS 95% CI crossed 1; prespecified one-sided test.
ConquerRSV: placebo-controlled efficacy in older adults; short follow-up.